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In addition, their expression is upregulated in endometriotic lesions

Glycine-Histidine-Lysine (GHK), a naturally occurring tripeptide present in human plasma and urine, possesses potent antioxidant properties

The F-box protein slimb controls the levels of clock proteins period and timeless

Although there are promising novel therapeutic approaches, further research is needed to better understand the disease mechanisms, develop therapies that target difficult to reach tissues and create adjuvant therapies that address secondary cellular processes caused by the enzyme deficiency

At the same time, prebiotics, as indigestible food components, further enhance the role of probiotics by selectively stimulating the growth of specific beneficial bacteria in the gut (Sanders et al., 2019